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    Welcome to the new era of microbiome innovation

    We exist 100% for the microbiome. For practitioners. For patients. For the next frontier of health. Our product range is built on evidence. Every formula is rooted in science and designed to support microbiome balance for "whole-istic" health across diverse categories.

Welcome to the new era of microbiome innovation

We exist 100% for the microbiome. For practitioners. For patients. For the next frontier of health.

    A smarter way to support gut health

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    100% spore-based probiotic

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    Supports gut reconditioning*

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    Clinically tested to maintain a healthy gut microbiome*

    How it works

    The spore advantage

    Bacillus spores stay dormant in harsh conditions, then activate where they're needed.

    Dormant

    Protected by a natural spore shell, they survive stomach acid, heat & shelf storage

    Active

    Reach the intestines and shift to their active, vegetative form

    Recondition

    Promote microbial diversity & key species with high survivability

    Meet Mega SporeBiotic

    100% spore-based, 5-strain probiotic designed to survive the journey through digestion.

    Resilient Bacillus spores help support a healthy gut barrier, promote microbial diversity, and fuel a more balanced, resilient gut microbiome.

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    STRAIN RESILIENCE
    EXCEPTIONAL SURVIVAL
    QUORUM SENSING MODE OF ACTION
    MICROBIOME RECONDITIONING
    REAL WORLD EVIDENCE (300 PARTICIPANTS)
    • Vegan/Vegetarian

    • Non-GMO

    • Gluten-Free

    • Free From 9 Major Allergens

    • Made In The U.SWith GloballySourced Ingredients

      • Haroldo Magarinos

        ND, DDS

      • Christine Maren

        DO

      • Jacquel Patterson

        MD

      • Anna Cabeca

        DO, FACOG

      • Dushyant Viswanathan

        MD

         

        Better research. Real results.

        Mega SporeBiotic provided relief for occasional abdominal discomfort and supported elimination and digestive health in study subjects.

        Ten peer-reviewed studies found that Mega SporeBiotic promotes:

        Greater microbial diversity* Health-supportive gut bacterial growth (and thus, short-chain fatty acid production)*

        Helps maintain a healthy balance of naturally occurring flora*

        Robust whole body benefits

        Promotes microbial diversity*

        Antioxidant producing*

        Supports the gut barrier /1ining*

        Promotes immune function*

        • Bacillus Indicus HU36

          Produces vitamins and carotenoids, including astaxanthin, zeaxanthin, and a- carotene.

        • Bacillus subtilis HU58

          Secretes antimicrobial compounds, supports healthy liver function, and produces nattokinase and vitamin K2.

        • Bacillus clausii SC-109

          known for supporting a strong and balanced immune system.

        • Bacillus coagulans SC-208

          Produces L+ lactic acid to support immune and gut defense and promotes B- galactosidase (lactase) activity to aid lactose breakdown.

        • Bacillus licheniformis SL-307

          Aids protein digestion and B-vitamin synthesis.

          Suggested use

          • Week 1: 1 capsule every other day.
          • Week 2: 1 capsule per day.
          • Week 3+: 2 capsules per day, with food, or as recommended by your healthcare practitioner.
          • If you are pregnant or nursing, taking any medication, or have a medical condition, always consult your doctor before using this product. Keep out of reach of children. Do not use if safety seal is broken or missing. No refrigeration required.
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          FAQ

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          Are Microbiome Labs products third-party tested and independently verified?

          Microbiome Labs follows quality and testing protocols to help ensure products meet label claims and quality standards. For more information, refer to our quality page.

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          Can I take multiple Microbiome Labs products together?

          Many people stack microbiome supplements, but the best combination depends on your goals and tolerance. A smart approach is to discuss your regimen with your healthcare practitioner to make sure it's right for your needs.

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          What is the science behind Microbiome Labs products?

          We pride ourselves on the scientific backing of our products. MegaSporeBiotic alone has 10 human clinical trials on the finished formula. We conduct Real World Evidence studies on our finished products, and our ingredients are some of the most studied probiotics in the world. As part of the Novonesis family, we have access to well-researched bacterial strains and feature them in almost all our formulas.

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          What is the difference between a probiotic, prebiotic, and digestive enzyme?

          Probiotics are beneficial microorganisms. Prebiotics are fibers or compounds that help nourish beneficial microbes. Digestive enzymes help break down food components like proteins, fats, and carbohydrates to support digestion. Many people use them together depending on their goals, diet, and sensitivity.

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          Are your products gluten free?

          Gluten free status varies by product. Check the label and product page for gluten free statements and ingredient disclosures. If you have questions, talk to your healthcare provider.

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          What is the shelf life of your products?

          Shelf life varies by product. You'll find a "Best by" date printed on every bottle or package. Most of our products have a 24-month shelf life from the date of manufacture. Store them as directed on the label to maintain freshness and potency through that date.

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          What makes MegaSporeBioticTM different from traditional probiotics?

          Traditional probiotics rely on fragile strains that are sensitive to heat, moisture, and stomach acid. MegaSporeBiotic™ is a spore-based probiotic. It uses spore-forming strains chosen for their resilience and compatibility with the digestive environment, so beneficial microbes can reach the gut and support a balanced microbiome.

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          Are probiotics safe to take during pregnancy and breastfeeding?

          In general, probiotics are widely used, but pregnancy and breastfeeding are unique physiological states. It’s best to consult your OB/GYN, midwife, or healthcare provider before starting any supplement to ensure it’s appropriate for your individual needs.

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          Why do our products have a QR code?

          The QR code lets you confirm your product is authentic, safe, and sourced directly from us. Scan it to verify your product is genuine, check that it hasn't been copied or tampered with, and know it was made to our quality and safety standards.